Specialty Nutrients in ArthraPro

ArthraPro is the most comprehensive, natural joint formula available today and is capable of breaking the osteoarthritis cycle, repairing damaged cartilage, and strengthening muscles, ligaments and tendons – the supporting structures for your pet’s joints.

Aliva® Joint Support Complex

ArthraPro contains a proprietary Aliva® Joint Support Complex along with multiple key ingredients that work together to reverse the conditions that allow joint damage to become a chronic destructive, debilitating disease.

GlycoMarine™ – New Zealand Green Lipped Mussel Extract (GLME)

GlycoMarine™ is a freeze-dried powder prepared by patented process from a liquid extract of the Green Lipped Mussel Perna canaliculus. Unlike the commonly used Green Lipped Mussel Powders, GlycoMarine™ is a proven Cox-2 inhibitor similar in strength to most NSAID drugs.

Clinical Use:

GlycoMarine™ is currently used for the treatment of both rheumatoid and osteoarthritis in both human and animal subjects. It is classified as a chondroprotective nutraceutical and has the backing of 30 years of peer-reviewed research to support its pharmacological activity. The main reason for its extensive use is that it is an effective, natural anti-inflammatory with selective cyclooxygenase (COX-2) inhibitory properties that can be used on a long-term basis without the complication of any adverse side effects.

Pharmacological Functions:

  1. Anti-inflammatory – GlycoMarine™ inhibits both the cyclooxygenase and 5-lipoxygenase enzyme cascades with COX-2 selectivity. These functions are a response to the lipid component of the extract.
  2. GlycoMarine™ also inhibits a number of pro-inflammatory neutrophil functions including: neutrophil emigration, catabolic cytokines and the mediation of T-lymphocyte activity. These functions are a response to the carbohydrate component of the extract.
  3. Chondroprotection – GlycoMarine™ inhibits the catabolic degradation of articular cartilage and enhances the lubrication and buffering of arthritic joints. GlycoMarine™ provides natural Chondroitin and Hyaluronic Acid to support rapid healing and the return to optimum joint health. This activity is a response to the amino acid and glycosaminoglycan content of the extract.
  4. Gastroprotection – GlycoMarine™ protects the stomach unlike the ulcerogenic effects of non-steroidal anti-inflammatory drugs. This activity is a response to the lipid component of the extract.
  5. Pain relief – GlycoMarine™ relieves pain as a result of its natural anti-inflammatory and chondroprotective properties.

Note: By directly supplying Chondroitin and Hyaluronic Acid, GlycoMarine™ far surpasses Glucosamine when it comes to providing joint matrix components.

Type II Collagen

Type II Collagen is the major component of articular joint cartilage. Our Aliva® Joint Support Complex uses a unique, patented Type II Collagen derived exclusively from avian (Chicken) sternum cartilage. The specific manufacturing process optimizes the low molecular weight for maximum absorption without affecting its beneficial effects on joint health. Aliva® Joint Support Complex Type II collagen has a protein content of 65-70% with 18 specific long chain amino acids that remain intact ensuring the animal’s natural enzymes will recognize the precise genetic code for maximum assimilation and ultimate joint health results.

This Type II Collagen additionally supplies 25 – 30% naturally occurring mucopolysaccharides consisting of natural Chondroitin and Hyaluronic acid that are essential for the production of collagen cells and the biosynthesis of synovial fluid.

Research has demonstrated that our Aliva® Joint Health collagen works with the immune system to deactivate collagen-specific T cells which prevents the secretion of collagenase enzymes responsible for the breakdown of joint collagen. Once the immune system is alerted to stop attacking its own collagen, the numbers of inflammatory cytokines that trigger the damaging inflammatory reaction are decreased resulting in a slowing and then stopping of the destructive cycle of collagen erosion in the joints. This allows the body the opportunity to ultimately rebuild cartilage and heal affected joints.

HMB (β-hydroxy-β-methylbutyrate)

HMB is a unique nutritional ingredient produced naturally in the body from the essential amino acid Leucine. As one of the essential amino acids the dog is unable to synthesize it. Therefore, it must be obtained either through diet or supplementation.

HMB is a fifth generation metabolite of Leucine, which functions at a much higher level in the body as a primary component or building block of muscle tissue. In situations where metabolic demand is high as in rigorous exercise, disease processes, or rehabilitation – the body cannot supply sufficient amounts of HMB to meet specific tissue needs. In these situations, dietary supplementation of HMB has been shown to be highly advantageous in maintaining maximum muscle size and strength, preventing muscle wasting and reversing muscle atrophy.

Research Studies:

Both human and animal studies have shown that HMB is a critical element in preserving muscle size and function and is capable of slowing the loss of muscle associated with stress and disease. It has also been proven capable of increasing muscle strength and functional ability by up to 33% in adult and senior animals.

HMB strengthens the muscles that support joint stability helping animals return to a more active, flexible and mobile state. As such, it is considered to be a vital component in osteoarthritic conditions. HMB has also been shown in numerous human and animal studies to be completely safe. Ross Labs uses HMB in their human post-operative hip replacement protocols to improve recovery time and has recently added HMB to its popular senior drink Ensure.


100% Avian Eggshell Membrane & Chicken Sternum Cartilage

U.S Patent #8,344,106 B1

TendoGuard™ is a proprietary (patented) dietary supplement formula containing a perfect balance of collagen Types I, II, V, X, Hyaluronic Acid, Chondroitin Sulfate, and Mucopolysaccharides.

TendoGuard™ naturally contains anti-inflammatory and antibacterial compounds to support tendon recovery and to maintain healthy and strong mechanical properties of tendon, bone, and joint functions.

Canine ArthraPro

Feline ArthraPro

By Clayton Bolinger
February 28, 2023